DOXIMAC-C

DOXIMAC-C is a high-quality water-soluble veterinary formulation designed for the effective treatment of respiratory and gastrointestinal infections in livestock and poultry. The powerful combination of Doxycycline HCl, Tylosin Tartrate, Colistin Sulfate, and Bromhexine provides broad-spectrum antibacterial coverage along with mucolytic support to improve respiratory function and mucus clearance.

Composition

Each kilogram contains:
Tylosin Tartrate – 100 g
Doxycycline HCl – 200 g
Colistin Sulfate – 400 MIU
Bromhexine – 3 g

Description

The combination of tylosin and doxycycline provides additive antibacterial activity. Doxycycline belongs to the tetracycline group and acts bacteriostatically against many Gram-positive and Gram-negative bacteria including Bordetella, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus, and Streptococcus species. It is also effective against Chlamydia, Mycoplasma, and Rickettsia species. Doxycycline inhibits bacterial protein synthesis and has a strong affinity for lung tissue, making it highly effective for respiratory infections.

Tylosin is a macrolide antibiotic with bacteriostatic activity against several Gram-positive and Gram-negative bacteria including Campylobacter, Pasteurella, Staphylococcus, Streptococcus, Treponema species, and Mycoplasma.

Bromhexine and its metabolite ambroxol are widely used for their mucolytic properties. They help stimulate surfactant release, regulate mucus production, and facilitate expectoration for improved respiratory function.

Colistin is a polymyxin antibiotic with bactericidal activity against Gram-negative bacteria including E. coli, Haemophilus, and Salmonella species. It disrupts bacterial cell membranes and neutralizes endotoxins produced by Gram-negative bacteria.

Indications

DOXIMAC-C is indicated for the treatment of gastrointestinal and respiratory infections caused by tylosin and doxycycline sensitive micro-organisms including Bordetella, Campylobacter, Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus, Streptococcus, and Treponema species in calves, goats, poultry, and sheep.

Contra indications

Do not use in animals hypersensitive to tetracyclines, tylosin, colistin, or bromhexine.
Avoid administration to animals with seriously impaired hepatic function.
Do not administer concurrently with penicillins, cephalosporins, quinolones, or cycloserine.
Not recommended for animals with active microbial digestion.

Side effects

Discoloration of teeth may occur in young animals.
Hypersensitivity reactions may occur.
Diarrhoea may occasionally develop during treatment.

Dosage

For oral administration.

Calves, sheep and goats

Twice daily, 5 g per 100 kg body weight for 3–5 days.

Poultry

1 g per 2–4 litres of drinking water for 3–5 days.

Withdrawal times

For meat:
Calves, goats, and sheep: 14 days
Swine: 8 days
Poultry: 7 days

Packaging

Jar of 1000 g
Jar of 500 g

Special Note

Use freshly prepared medicated water daily for best results.
Not intended for animals hypersensitive to the active ingredients.

Specifications

What’s in the Box

• 12 x DOXIMAC-C Water Soluble Powder