COLIS 500
COLIS 500 is a professional veterinary antimicrobial formulation containing Colistin Sulphate, a potent polypeptide antibiotic effective against Gram-negative bacterial infections. It is widely used in poultry and livestock for the treatment and control of enteric infections caused by susceptible bacteria such as E. coli and Salmonella. Its targeted bactericidal action helps support rapid recovery and improved animal performance.
COLIS 500 is a high-quality veterinary antibiotic formulation containing Colistin Sulphate, a well-established antimicrobial agent from the polymyxin group. It is specifically designed to combat Gram-negative bacterial infections affecting poultry and livestock, particularly those involving the gastrointestinal tract.
Its strong bactericidal activity and effectiveness against important enteric pathogens make COLIS 500 a valuable component of modern veterinary disease management programs.
Composition
Each gram Contains:
Colistin Sulphate…..BP…..5.00MIU
Product complies Prix Specification
Description
Colistin Sulphate is a polypeptide antibiotic belonging to the polymyxin class of antimicrobials. It exhibits potent bactericidal activity against a wide range of Gram-negative bacteria by disrupting the integrity of the bacterial cell membrane.
The antibiotic interacts with phospholipids and lipopolysaccharides within the bacterial outer membrane, causing leakage of cellular contents and rapid bacterial death.
Colistin is particularly effective against Gram-negative pathogens such as E. coli, Klebsiella, Pseudomonas, Salmonella, and other susceptible microorganisms. Due to its limited absorption from the gastrointestinal tract following oral administration, it provides high concentrations within the intestinal lumen, making it especially useful for managing enteric bacterial infections.
Indications
COLIS 500 is indicated for the treatment and control of bacterial infections caused by Colistin-sensitive Gram-negative organisms, including:
Colibacillosis (E. coli infections)
Salmonellosis
Enteric bacterial infections
Gastrointestinal infections caused by susceptible Gram-negative bacteria
Mixed infections involving Colistin-sensitive pathogens
Suitable for poultry and livestock under veterinary supervision.
Contra indications
Do not use in animals known to be hypersensitive to Colistin or polymyxin antibiotics.
Use according to veterinary recommendations and applicable local regulations.
Side effects
When administered according to recommended guidelines, adverse effects are generally uncommon. Hypersensitivity reactions may occur in sensitive animals.
Dosage
Orally via drinking water or with milk replacer
Calves, sheep and goats
0.2 gm per 10 kg body weight in water / milk replacer for 3-5 days.
Poultry / Pet birds
1 gm in 10 liters of drinking water for 3~5 days.
Withdrawal times
Observe withdrawal periods specified on the product label and comply with local regulatory requirements.
Packaging
Available in veterinary packaging sizes.
Special Note
Prepare fresh medicated water daily during treatment.
Ensure adequate water intake throughout the treatment period.
Use responsibly under veterinary supervision to support effective antimicrobial stewardship.
Specifications
| Feature | Details |
|---|---|
| Product Name | COLIS 500 |
| Active Ingredient | Colistin Sulphate |
| Product Type | Veterinary Antibiotic |
| Drug Class | Polymyxin (Polypeptide Antibiotic) |
| Primary Action | Bactericidal Activity Against Gram-Negative Bacteria |
| Target Organisms | E. coli, Klebsiella, Pseudomonas, Salmonella, and other susceptible Gram-negative bacteria |
| Target Species | Poultry and Livestock |
| Indications | Colibacillosis, Salmonellosis, and enteric bacterial infections |
| Administration | As directed by a veterinarian |
| Usage | Veterinary Use Only |
What’s in the Box
- 12 x COLIS 500 Water Soluble Powder
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